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You can buy Amaryl without prescription as the best medicamental agent with antidiabetic activity. The main ingredient is chiefly Glimepiride. This remedy generally possesses by the strong hypoglycemic pharmacological action. The medicant actively stimulates the secretion and deblocking of the insulin be beta-cells of the pancreas. The drug also improves the postprandial insulin/C-peptide on an empty stomach. The medical agent generally increases the peripheral tissues’ apprehensibility to insulin (the extrapancreatic activity). The hypoglycemic effect mostly reaches its maximum over two-three hours and it is prolonged more than twenty-four hours. This effect is stabilized during the next two weeks. The medical remedy chiefly decreases the developing risk of retino-, neuro- and nephropathy.

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  • pancreatic diabetes the second type (monotherapy);
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This officinal agent is usually contraindicated (or limited for its taking) under

  • breast-feeding;
  • some sicknesses of the person’s liver in stage of sharpening;
  • edematous syndrome;
  • age till eighteen years;
  • pancreatic diabetes of the first type;
  • heavy cardiac intolerance;
  • disturbances of the kidneys’ some functions;
  • gestation;
  • uterine bleedings;
  • diabetic ketoacidosis;
  • anemia;
  • hyperresponsiveness to the main active substance;
  • several others.

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