Paxil and its pharmacological actions
Paxil refers to the SSRI antidepressants. The basis component of the drug (paroxetine) does not interfere with the function of the cardiovascular system, has no inhibitory effect on the central nervous system and does not affect psychomotor functions. Preparation does not cause changes in both blood pressure and also heart rate, and brain electrical activity (provided that the receiving medication the patient has no health problems above organ systems). Medicine is not capable of inducing sleep disorders when morning administration. On the contrary, when taken regularly remedy quality of sleep is improved. It becomes possible for patient to order Paxil online overnight no rx nowadays. Psychotropic medication activity is expressed in tangible antidepressant and anti-anxiety effects.
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Medicament is mainly indicated for:
- any depression, including reactive and endogenous depression, severe depression coupled with anxiety disorders;
- therapy, prevention of OCD in children and adolescents 7 - 17 years, and adults;
- treating of panic disorder (including with agoraphobia). Drug retains its effectiveness and prevents disorder re-occurrence;
- social phobia in children and also adolescents 7 - 17 years, and adults. The effectiveness of paroxetine in the treatment of this phobia is unabated throughout the year;
- generalized anxiety disorder. In this case, remedy also prevents return disorder, and its efficiency is not reduced during the year;
- treatment status of post traumatic stress.
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Receiving of medication is contraindicated if:
- patients under 18 years of age;
- during lactation;
- with the use of pimozide, MAO inhibitors or tryptophan, and thioridazine. Similarly, MAO inhibitors can be applied not earlier than 2 weeks after stopping treatment with remedy;
- in addition, attention should be paid to individual sensitivity to the antidepressant (in case of hypersensitivity should abandon its use). To buy Paxil without prescription is better after close examination of patient by doctor.
Ways of applying and dosages
People prefer to order the widely spread package form of Paxil 10 mg 120 pills. In the treatment of adult depression standard therapeutic dosing is 20 mg per day. However, if the remedy has insufficient impact on the condition of the patient, may increase the dosage up to the limit of 50 mg. Not abruptly increase the dose recommended by the gradual addition of 10 mg per week. To increase dosage is recommended after 2-3 weeks after receiving the medicine.
In the therapy of OCD syndrome patient should begin to take the pill in an amount of 20 mg by day. Then it is followed to enhance weekly 10 mg. Under treating panic disorder the average adult dosage is 40 mg / day. To avoid the possible exacerbation of symptoms of the disorder, it is necessary to begin with a daily dose amount of 10 mg. Weekly increase in the dose of 10 mg should be stopped upon reaching effect. The maximum possible dose is 60 mg per day. The treatment must be long sufficient to ensure the removal of symptoms. This period may last for several months in the treatment of depression and also obsessive-compulsive when and panic disorders - even longer. As with other psychotropic drugs, avoid sudden withdrawal of the drug.
Paxil collateral effects and special directions
When receiving preparation in patient can be observed:
- nervousness, emotional lability, insomnia;
- headaches, migraines;
- drowsiness, fatigue;
- tremor, myoclonus, convulsive manifestations;
- worsening depression, depersonalization;
- excessive sweating;
- dry mouth;
- anemic manifestations, lymphadenopathy, leukopenia;
- reduction of pressure, orthostatic hypotension (in rare cases);
- bruising, bleeding;
- decreased libido;
- change in fertility as a result of violations of sperm quality;
- impotence, abnormal ejaculation;
- loss of appetite, violations of the chair;
- nausea, vomiting;
- serotonin syndrome;
- increase in body weight;
- cholestasis, hepatotoxicity;
- sinusitis, rhinitis;
- swelling of the face;
- compulsive disorder, suicidal thoughts;
- aggression, hostility;
- galactorrhea, hyponatremia;
- acute glaucoma (rare), visual disturbances;
- urticaria, nonspecific rash, photosensitivity;
- sinus tachycardia and so on.
If you are planning the ordering Paxil online it is better to consult a doctor. The medication is not prescribed to children because of the presence in this age group, significant side effects as autoagressive behavior, increased depression, and suicidal ideation in adolescents.
Negative effects can appear under the concomitant applying of different medications as:
- pimozide, tryptophan, MAO inhibitors are incompatible with paroxetine. Tryptophan enhances sweating and nausea during co-administration, promotes the "serotonin syndrome" development;
- when combined therapy with tramadol, lithium, SSRI antidepressants, preparations also seen the syndrome development. Paxil increases alcohol-containing medicines effects and reduces digoxin, and tamoxifen effectiveness;
- dosage adjustment is required for the appointment of propafenone, procyclidine, encainide, metoprolol, flecainide, thioridazine, perphenazine, tricyclic antidepressants, and codeine.
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