Strattera and its pharmacological actions
Strattera relates to sympathomimetics with central action. The active ingredient atomoxetine refers to highly potent inhibitors of presynaptic norepinephrine vectors and is not a derivative of amphetamine. Medicine has minimal affinity for other noradrenergic receptors or neurotransmitters transporters. It is not a stimulant. In clinical trials, cases under drug’s cancellation there are no amplification of symptoms or any adverse events that are associated with withdrawal syndrome. After receiving atomoxetine inside is rapidly and almost fully absorbed, well distributed in the body. The time to reach maximum serum concentration is 1-2 hours. Medication is prescribed regardless of the meal. To order Strattera online overnight no rx is possible for patients all day nowadays.
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There are many various products in addition to stimulant that can be applied in the treatment of ADHD. Strattera operating principle is based on the increase in the content of norepinephrine in the brain tissue (very important chemical substances). This weakens the symptoms of disorder as:
- lack of concentration;
- excessive restlessness;
- other similar conduct disorders.
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Parents may buy Strattera online pharmacy for their children.
The contra-indications for remedy’s application are:
- closure glaucoma;
- simultaneous use of MAO inhibitors;
- severe damage to the heart;
- hypersensitiveness to the medicament.
In order to buy Strattera without prescription you have to receive the doctor’s consultation. People use carefully preparation if they have tachycardia, hypertension, cardio vascular diseases, sudden cardiac death, severe physical congestion, while taking stimulants, a family history of stroke patients, seizures, and also for conditions that may lead to hypotension. The following symptoms were noted in people receiving atomoxetine as agitation, anxiety, panic attacks, irritability, insomnia, impulsivity. Patients taking these pills are required to be under close surveillance in relation to the development of these symptoms. Parents and relatives must closely monitor the appearance of above symptoms and also suicidal thoughts in children and adolescents applying the remedy, and immediately report it to doctor. Atomoxetine cause eye irritation. In case of contact with the capsule contents into the eyes, immediately flush eyes with water. Hands and contact surfaces must be rinsed with water.
Ways of applying and dosages
Strattera 10mg 360 pills are taken orally 1 time/day, in the morning. In case of adverse effects while taking the preparation once a day, patients may recommend applying twice per day, dividing the dose of morning and reception in the late afternoon. Removing the drug does not require the gradual reduction in dosage. The recommended initial daily dose Strattera is about 500 mcg/kg and increased to a therapeutic daily dosing approximately 1.2 mcg/kg no sooner than 3 days. If there is no improvement in the condition of the patient, the total daily dose can be increased to a maximum dose of 1.8 mcg/kg no sooner than 2-4 weeks after you start taking this product. Medicament’s therapy should be carried out under the medical supervision.
Strattera collateral effects and special directions
Adverse events are most commonly associated with taking medicine:
- digestive system: very common (> 10%) - abdominal pain, decreased appetite, vomiting; often (10.1%) - constipation, indigestion, nausea (9%), anorexia. These side effects are temporary and usually do not require discontinuation of the drug;
- cardio-vascular system: (0.1-1%) - palpitations, sinus tachycardia;
- CNS side effects: somnolence (including sedation); often - irritability, mood swings, dizziness; sometimes - early morning awakening;
- part of the vision: frequent (1-10%) – mydriasis;
- dermatological reactions: dermatitis, rash; sometimes itching;
- other: often (10.1%) - the flu, fatigue, weight loss; sometimes (0.1-1%) - weakness.
Taking the drug may be accompanied by sleepiness. Therefore, patients ordering Strattera online, with caution should be exercised in the management of hazardous mechanical means, including car, as long as they are not sure that atomoxetine does not cause any disturbances.
Preparation can cause unfavorable results:
- simultaneous application of Strattera with agonist beta2 adrenergic receptor (salbutamol, fenoterol, clenbuterol, salmeterol, and others.) may enhance their effects on the cardiovascular system; following sequence should be used with caution;
- remedy does not cause clinically significant inhibition or induction of cytochrome P450 isoenzymes, including CYP3A, CYP1A2, CYP2D6, or CYP2C9;
- due to the possible effect on blood pressure medicine must be taken with caution in combination with remedies affecting blood pressure;
- preparations containing magnesium hydrochloride, aluminum hydroxide, aluminum hydroxide and magnesium omeprazole does not affect the medication’s bioavailability;
- drugs affecting the secretion of norepinephrine should be applied with caution at the same time with Strattera because of the potential gain or synergistic pharmacological effect;
- preparation does not affect the binding of warfarin to plasma albumin, acetylsalicylic acid, or phenytoin and diazepam.
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